Detection of foot-and-mouth disease viruses from the A/AFRICA/G-I genotype in the Sultanate of Oman

Ahmed Al-Rawahi W., Al-Riyami B., Ibrahim Elshafie E., Baqir S., Al-Ansari A., Wadsworth J., M. Hicks H., J. Knowles N., Di Nardo A., P. King D., Zientara S., Al Salloom F.,  Sangula A., Bernelin-Cottet C. and Bakkali-Kassimi L., Preventive Veterinary Medicine 2023

doi: 10.1016/j.prevetmed.2023.106113


Leaderless foot-and-mouth disease virus serotype O did not cause clinical disease and failed to establish a persistent infection in cattle

Litz B., Sehl-Ewert J., Breithaupt A., Landmesser A., Pfaff F., Romey A., Blaise-Boisseau S., Beer M. and Eschbaumer M., Emerging Microbes & Infections 2024

doi: 10.1080/22221751.2024.2348526.


Host specific interplay between Foot-and-Mouth Disease Virus 3D polymerase and the type I interferon pathway

Sarry M, Caignard G, Dupré J, Zientara S, Vitour D, Bakkali-Kassimi L and Blaise-Boisseau S 2023 Viruses

doi: 10.3390/v15030666


Field evaluation of a safe, easy and low-cost protocol for shipment of samples from suspected cases of foot-and-mouth disease to diagnostic laboratories

Romey A, Ularamu-Hussaini G., Bulut A, Jamal-Syed M., Khan S, Ishaq M, Eschbaumer Ml, Belsham-Graham J., Bernelin-Cottet C, Relmy A, Gondard M, Benfrid S, Wungak-Yiltawe S., Hamers C, Hudelet P, Zientara S, Bakkali-Kassimi L and Blaise-Boisseau S 2023 TBED


Development of a primary cell model derived from porcine dorsal soft palate for foot-and-mouth disease virus research and diagnosis

Sarry M, Bernelin-Cottet C, Michaud C, Relmy A, Romey A, Salomez AL, Renson P, Contrant M, Berthaud M, Huet H, Jouvion G, Hägglund S, Valarcher JF, Bakkali Kassimi L, Blaise-Boisseau S. Microbiol. 2023.

doi: 10.3389/fmicb.2023.1215347


Application of the Nagoya Protocol to veterinary pathogens: concerns for the control of foot-and-mouth disease

Horsington J., Abbeloos E., Bakkali-Kassimi L., Boonsuya Seeyo K., Capozzo AV., Chepkwony E., Eblé P., Galdo-Novo S., Gizaw D., Gouverneur L., Grazioli S., Heath L., Hudelet P., Hyera JMK., Ilott M., King A., Lefebvre D., Mackay D., Metwally S., Mwiine FN., Nfon CK., Park M-K., Pituco EM., Rosso F., Simon F., Ularamu HG., Vermeij P., Vosloo W. and King DP.

doi: 10.3389/fvets.2023.1271434





Identification of diffusion routes of O/EA-3 topotype of foot-and-mouth disease virus in Africa and Western Asia between 1974 and 2019 - a phylogeographic analysis

Canini L, Blaise-Boisseau S, Wadsworth J, Nardo AD, Shaw A, Romey A, Relmy A, Bernelin-Cottet C, Salomez AL, Haegeman A, Ularamu H, Lefebvre D, De Clercq K, Mioulet V, Brocchi E, Pezzoni G, Nfon C, King D, Durand B, Knowles N, Kassimi LB, Benfrid S. 2022 Transbound Emerg Dis.

doi: 10.1111/tbed.14562.


Characterization of the O/ME-SA/Ind-2001d foot-and-mouth disease virus epidemic recorded in the Maghreb during 2014-15

Pezzoni G, Calzolari M, Foglia EA, Bregoli A, Nardo AD, Sghaier S, Madani H, Chiapponi C, Grazioli S, Relmy A, Kassimi LB, Brocchi E. 2022 Transbound Emerg Dis.

doi: 10.1111/tbed.14611


Molecular and Serological Epidemiology of Foot-and-Mouth Disease Virus in North Region of Cameroon

Dickmu S. , Awah-Ndukum J. , Aziwo N. , Sevidzem S. , Mouliom Mouiche M. , Rueda C. , Kassimi L. , Wade A. , Garabed R. , El-Yuguda A. , Rodriguez L. and Baba S. 2022 Advances in Microbiology

doi: 10.4236/aim.2022.1210040


Molecular Interplays with IFN Response and the Importance of the Model

Sarry, M.; Vitour, D.; Zientara, S.; Bakkali Kassimi, L.; Blaise-Boisseau, S. Viruses 2022


Le virus de la fièvre aphteuse : transmission, pathogenèse, diagnostic et surveillance

Sarry M., Romey A., Lefebvre D., Benfrid S., Dufour B., Durand B., Zanella G., De Regge N., Zientara S.; Bakkali Kassimi L. et Blaise-Boisseau S. 2022 Virologie

doi : 10.1684/vir.2022.0972



The history of foot-and-mouth disease virus serotype C: the first known extinct serotype?

Paton D J, Di Nardo A, Knowles N J, Wadsworth J, Pituco E M, Cosivi O, Rivera A M, Bakkali Kassimi L, Brocchi E, De Clercq K, Carrillo C,Maree F F, Singh R K, Vosloo W, Park M-K, Sumption K J, Ludi A B, King D P.   2021 Virus Evolution.


Selection and use of reference panels: a case study highlighting current gaps in the materials available for foot and mouth disease

Ludi A B, Mioulet V, Bakkali Kassimi L, Lefebvre D J, De Clercq K, Chitsungo E, Nwankpa N, Vosloo W, Paton D J & King D P.  2021 Rev. Sci. Tech

doi: 10.20506/rst.39.2.3089



The Antibody Response Induced FMDV Vaccines in Sheep Correlates with Early Transcriptomic Responses in Blood 

Jouneau L, Lefebvre D J, Costa F, Romey A, Blaise-Boisseau S, Relmy A, Jaszczysyn Y, Dard-Dascot C, Dejeans S, Versillé N, Guitton E, Hudelet P, Curet M, De Clercq K, Bakkali Kassimi L, Zientara S, Klonjkowski B and Schwartz-Cornil L. 2020  NPJ Vaccines.



Model of persistent foot-and-mouth disease virus infection in multilayered cells derived from bovine dorsal soft palate

Hägglund S, Laloy E, Näslund K, Pfaff F, Eschbaumer M, Romey A, Relmy A, Rikberg A, Svensson A, Huet H, Gorna K, Zühlke D, Riedel K, Beer M, Zientara S, Bakkali Kassimi L, Blaise‐Boisseau S, J.F Valarcher. 2020 Transbound Emerg Dis.



The antibody response induced FMDV vaccines in sheep correlates with early transcriptomic responses in blood

Jouneau L, Lefebvre DJ, Costa F, Romey A, Blaise-Boisseau S, Relmy A, Jaszczyszyn Y, Dard-Dascot C, Déjean S, Versillé N, Guitton E, Hudelet P, Curet M, De Clercq K, Bakkali Kassimi L, Zientara S, Klonjkowski B, Schwartz-Cornil I. 2020 NPJ Vaccines

doi: 10.1038/s41541-019-0151-3


FMD vaccine matching: Inter laboratory study for improved understanding of r1 values

Willems T, De Vleeschauwer A, Perez-Filgueira M, Li Y, Ludi A, Lefebvre D, Wilsden G, Statham B, Haas B, Mattion N, Robiolo B, Beascoechea Perez C, Maradei E, Smitsaart E, La Torre J, De Clercq K. 2020. J Virol Methods

doi: 10.1016/j.jviromet.2019.113786


Seroprevalence and molecular characterization of foot-and-mouth disease in Chad

Abdel-Aziz AI., Romey A., Relmy A., Gorna K., Laloy E., Métras R., Munoz F., Blaise-Boisseau S., Zientara S., Lancelot R., Bakkali Kassimi L.2020. Vet Med Sci.

Doi : 10.1002/vms3.206. PMID : 31845545



Serological and molecular epidemiology of foot-and-mouth disease viruses in agro-pastoralist livestock herds in the kachia grazing reserve, Nigeria

Ehizibolo DO, De Vleeschauwer AR, Haegeman A, Lefebvre D, Nwosuh CI, Umoh JU, Okolocha EC, Kazeem HM, Van Borm S, De Clercq K. 2019. Transbound Emerg Dis.

doi: 10.1111/tbed.13182



Proteogenomics Uncovers Critical Elements of Host Response in Bovine Soft Palate Epithelial Cells Following In Vitro Infection with Foot-And-Mouth Disease Virus


Pfaff F, Hägglund S, Zoli M, Blaise-Boisseau S, Laloy E, Koethe S, Zühlke D, Riedel K, Zientara S, Bakkali-Kassimi L, Valarcher JF, Höper D, Beer M, Eschbaumer M. 2019. Viruses 11 (1)


Reconstructing the Evolutionary History of Pandemic Foot-and-Mouth Disease Viruses: The Impact of Recombination within the Emerging O/ME-SA/Ind-2001 Lineage

Bachanek-Bankowska K, Di Nardo A, Wadsworth J, Mioulet V, Pezzoni G, Grazioli S, Brocchi E, Kafle SC, Hettiarachchi R, Kumarawadu PL, Eldaghayes IM, Dayhum AS, Meenowa D, Sghaier S, Madani H, Abouchoaib N, Hoang BH, Vu PP, Dukpa K, Gurung RB, Tenzin S, Wernery U, Panthumart A, Seeyo KB, Linchongsubongkoch W, Relmy A, Bakkali-Kassimi L, Scherbakov A, King DP, Knowles NJ.2018. Sci Rep 8 (1)


Development and validation of a foot-and-mouth disease virus SAT serotype-specific 3ABC assay to differentiate infected from vaccinated animals

Chitray M, Grazioli S, Willems T, Tshabalala T, De Vleeschauwer A, Esterhuysen JJ, Brocchi E, De Clercq K, Maree FF. 2018. J Virol Methods

doi: 10.1016/j.jviromet.2018.02.006


A Canine Adenovirus Type 2 Vaccine Vector Confers Protection against Foot-and-Mouth Disease in Guinea Pigs

De Vleeschauwer Annebel R., Xiaocui Zhou, David J. Lefebvre, Annabelle Garnier, Fleur Watier, Charly Pignon, Sandrine A. Lacour, Stephan Zientara, Labib Bakkali-Kassimi, Kris De Clercq, Klonjkowski B. 2018. Vaccine 36 (16)


Complete Genome Sequences of Five Foot-and-Mouth Disease Viruses of Serotype A Isolated from Cattle in Nigeria between 2013 and 2015

Vandenbussche F, Mathijs E, Ularamu HG, Ehizibolo DO, Haegeman A, Lefebvre D, De Vleeschauwer AR, Van Borm S, De Clercq K. 2018. Genome Announc

doi: 10.1128/genomeA.00039-18


Outbreak investigations and molecular characterization of foot-and-mouth disease viruses circulating in south-west Niger

Souley Kouato B, Elliot FM, King DP, Hyera J, Knowles NJ, Ludi AB, Mioulet V, Matlho G, De Clercq K, Thys E, Marichatou H, Issa S, Saegerman C. 2018. Transbound Emerg Dis.

doi: 10.1111/tbed.12642


Safe and Cost-Effective Protocol for Shipment of Samples from Foot-and-Mouth Disease Suspected Cases for Laboratory Diagnostic

A.Romey, A. Relmy, K. Gorna, E. Laloy, S. Zientara, S. Blaise‐Boisseau, et L. Bakkali Kassimi. 2018. Transbound Emerg Dis. 65 (1)


Complete Genome Sequences of Four Foot-and-Mouth Disease Viruses of Serotype South African Territories 1 (SAT 1), Topotype X, Isolated from Cattle in Nigeria in 2015

Vandenbussche F, Mathijs E, Ularamu HG, Ehizibolo DO, Haegeman A, Lefebvre D, Lazarus DD, Wungak YS, De Vleeschauwer AR, Van Borm S, De Clercq K. 2017. Genome Announc

doi: 10.1128/genomeA.01065-17


Laboratory validation of two real-time RT-PCR methods with 5'-tailed primers for an enhanced detection of foot-and-mouth disease virus

Vandenbussche F, Lefebvre DJ, De Leeuw I, Van Borm S, De Clercq K. 2017. J Virol Methods

doi: 10.1016/j.jviromet.2017.04.014


Foot-and-mouth disease virus serotype SAT1 in cattle, Nigeria

Ehizibolo DO, Haegeman A, De Vleeschauwer AR, Umoh JU, Kazeem HM, Okolocha EC, Van Borm S, De Clercq K. 2017 Transbound Emerg Dis.

doi: 10.1111/tbed.12629


Detection and Molecular Characterization of Foot and Mouth Disease Viruses from Outbreaks in Some States of Northern Nigeria 2013-2015

Ehizibolo DO, Haegeman A, De Vleeschauwer AR, Umoh JU, Kazeem HM, Okolocha EC, Van Borm S, De Clercq K. 2017. Transbound Emerg Dis.

doi: 10.1111/tbed.12602


Genetic Characterization of Serotypes A and Asia-1 Foot-and-Mouth Disease Viruses in Balochistan, Pakistan, in 2011

A.Ullah, S. M. Jamal, A. Romey, K. Gorna, M. A. Kakar, F. Abbas, J. Ahmad, S. Zientara, et L. Bakkali Kassimi. 2017. Transbound Emerg Dis.64 (5)


A Tale of Tails: Dissecting the Enhancing Effect of Tailed Primers in Real-Time PCR

Vandenbussche F, Mathijs E, Lefebvre D, De Clercq K, Van Borm S. 2016. PLoS One

doi: 10.1371/journal.pone.0164463


Establishment and Validation of Two Duplex One-Step Real-Time RT-PCR Assays for Diagnosis of Foot-and-Mouth Disease

K.Gorna, A. Relmy, A. Romey, S. Zientara, S. Blaise-Boisseau, et L. Bakkali-Kassimi. 2016.J Virol Methods 235


A Refined Guinea Pig Model of Foot-and-Mouth Disease Virus Infection for Assessing the Efficacy of Antiviral Compounds

De Vleeschauwer AR, Lefebvre DJ, Willems T, Paul G, Billiet A, Murao LE, Neyts J, Goris N, De Clercq K. 2014. Transbound Emerg Dis.

doi: 10.1111/tbed.12255


Establishment of Persistent Foot-and-Mouth Disease Virus (FMDV) Infection in MDBK Cells

Kopliku Lela, Anthony Relmy, Aurore Romey, Kamila Gorna, Stephan Zientara, Labib Bakkali-Kassimi, et Sandra Blaise-Boisseau. 2015. Arch Virol 160 (10)


The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family

van der Linden L, Vives-Adrián L, Selisko B, Ferrer-Orta C, Liu X, Lanke K, Ulferts R, De Palma AM, Tanchis F, Goris N, Lefebvre D, De Clercq K, Leyssen P, Lacroix C, Pürstinger G, Coutard B, Canard B, Boehr DD, Arnold JJ, Cameron CE, Verdaguer N, Neyts J, van Kuppeveld FJ. 2015. PLoS Pathog

doi: 10.1371/journal.ppat.1004733


A thiazepino[4,5-a]benzimidazole derivative hampers the RNA replication of Eurasian serotypes of foot-and-mouth disease virus

Lefebvre DJ, De Vleeschauwer AR, Goris N, Van Borm S, Chimirri A, Monforte AM, Valdazo-Gonzalez B, King DP, Neyts J, De Clercq K. 2014. Biochem Biophys Res Commun.

doi: 10.1016/j.bbrc.2014.11.023


In vitro surrogate models to aid in the development of antivirals for the containment of foot-and-mouth disease outbreaks

Osiceanu AM, Murao LE, Kollanur D, Swinnen J, De Vleeschauwer AR, Lefebvre DJ, De Clercq K, Neyts J, Goris N. 2014. Antiviral Res.

doi: 10.1016/j.antiviral.2014.02.009


Application of a cell-based protease assay for testing inhibitors of picornavirus 3C proteases

van der Linden L, Ulferts R, Nabuurs SB, Kusov Y, Liu H, George S, Lacroix C, Goris N, Lefebvre D, Lanke KH, De Clercq K, Hilgenfeld R, Neyts J, van Kuppeveld FJ. 2014. Antiviral Res.

doi: 10.1016/j.antiviral.2013.12.012


Proof of concept for the inhibition of foot-and-mouth disease virus replication by the anti-viral drug 2'-C-methylcytidine in severe combined immunodeficient mice

Lefebvre DJ, De Vleeschauwer AR, Goris N, Kollanur D, Billiet A, Murao L, Neyts J, De Clercq K. 2014. Transbound Emerg Dis.

doi: 10.1111/tbed.12069


The use of serosurveys following emergency vaccination, to recover the status of "foot-and-mouth disease free where vaccination is not practised"

Paton DJ, Füssel AE, Vosloo W, Dekker A, De Clercq K. 2014. Vaccine

doi: 10.1016/j.vaccine.2014.10.064


First Isolation and Molecular Characterization of Foot-and-Mouth Disease Virus in Benin

K.Gorna, E. Houndjè, A. Romey, A. Relmy, S. Blaise-Boisseau, M. Kpodékon, C. Saegerman, F. Moutou, S. Zientara, et L. Bakkali Kassimi. 2014. Vet Microbiol 171 (1)